Gene Linked to Better Mesothelioma Cancer Prognosis


An increasing number of cancer treatments involve gene therapy and genetic testing and mesothelioma cancer is no different, as patients with a specific gene have recently been found to have a better than average mesothelioma prognosis.

Medical researchers have found that the BAP1 gene mutation — a hereditary or inherited gene mutation — may have a longer mesothelioma cancer survival rate.

Mesothelioma cancer can take several forms, impacting different areas of the body such as the lungs or the peritoneal cavity. But this form of cancer is known to be fast moving with a poor prognosis, as only 4 in 10 patients survive for longer than one year post-diagnosis and less than 10% survive for five years after diagnosis. So this new gene mutation and its impact on the mesothelioma prognosis is very welcome news.

How Does the BAP1 Gene Mutation Impact Mesothelioma Cancer Survival?

The BAP1 gene has been found to have tumor suppressant properties. A mutation in this critical gene can therefore increase a person’s risk of developing cancer, such as mesothelioma. But it’s not all bad news, as a Wake Forest University School of Medicine research study has found that the gene mutation can actually be beneficial for mesothelioma patients.

Formally known as the BRCA1 Associated Protein 1 gene, the BAP1 gene produces a protein that suppresses tumor growth. Without this protein, an individual may have a higher cancer risk.

But this study revealed that individuals with the gene mutation actually had a better mesothelioma prognosis because they were more likely to develop mesothelioma cancer (or another form of cancer) at a younger age, which results in a much higher chance of successful treatment and longer term survival.

In fact, many individuals with the BAP1 gene mutation now undergo routine cancer screenings, starting at a much younger age, which bodes well for an early diagnosis and a much better prognosis overall.

The study participants found to have the hereditary BAP1 gene mutation were also more likely to get peritoneal mesothelioma cancer, which has a better survival rate when compared to pleural mesothelioma lung cancer.

Finding Resources and Help After a Diagnosis of Mesothelioma Cancer

Following a mesothelioma cancer diagnosis, patients and their families are left very frightened and facing many questions. Mesowatch is there to provide you with a full range of mesothelioma and asbestos exposure resources, information and access to experienced mesothelioma attorneys and asbestos lawyers who can provide you with the guidance you need.

Whether you with to take action with an asbestos exposure lawsuit or wish to seek financial compensation with a mesothelioma lawsuit, information at will provide you with critical steps to take action with your unfortunate diagnosis. Call today for a free and confidential legal consultation.